All drugs of this group are well distributed in the body, penetrating (except cefoperazone) by HEB and may be used to treat infections of the CNS. Proteus spp, Klebsiella spp., Citrobacter whacked Providentia spp., Serratia spp., Yersinia spp., Morganella spp. Method of production of drugs: powder for Mr injection of 0.25 g to 0.5 g in 1.0 g of 2,0 g vial. With activity on staphylococci inferior drugs and second generations, but on the streptococcus and pneumococcus Ceftriaxone and cefotaxime over other cephalosporins and act on the most penitsylinorezystentnyh strains. Tsefazydym and cefoperazone are active against P.aeruginosa. coli, Klebsiella spp., Proteus mirabilis, Providencia spp., Proteus rettgeri; gram (+) aerobic: Staph. agalactiae); anaerobes: gram (+) and Gram (-) cocci (including Peptococcus species and PeptoStr.), Gram (+) bacteria (including species Clostridium) and gram (-) bacteria (including Bacteroides species and Fusobacterium), Propionibacterium spp; other m / c: Vorrelia burgdorferi. (Including Klebsiella pneumoniae), Proteus mirabilis, Proteus vulgaris, Morganella morganii (Proteus morganii), Proteus rettgeri, Providencia spp., Enterobacter spp., Citrobacter spp., Serratia spp., Salmonella spp., Shigella spp., Yersinia enterocolitica, Pasteurella multocida, Acinetobacter spp., Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae (including ampitsylinrezystentni strains), Haemophilus parainfluenzae (including ampitsylinrezystentni strains), MoAb Transcendental Meditation Staph. Cefotaxime and ceftazidime displayed the kidneys, Ceftriaxone and cefoperazone whacked kidneys and liver. Contraindications to the use of drugs: hypersensitivity to cephalosporins, penicillins. Side effects and complications here the use of drugs: Candida overgrowth during the long, eosinophilia, positive test Kumbsa, thrombocytopenia, leukopenia, hemolytic anemia, skin rash, hives, itching, drug fever, serum sickness, anaphylaxis, headache, whacked diarrhea, nausea, abdominal pain, vomiting, pseudomembranous colitis; Transient increase ALT, AST, LDH, jaundice, hepatitis, polymorphic erythema, CM Stevens-Johnson toxic epidermal necrolysis (ekzantematoznyy necrolysis). Indications for use drugs: upper respiratory tract infection: otitis media, sinusitis, tonsillitis and pharyngitis, respiratory tract infections: pneumonia, bronchitis and aggravation G hr. The main pharmaco-therapeutic action: bactericidal action; resistant to most beta-lactamases and are active against a whacked here of Gram whacked and Gram (-) whacked / s; bactericidal action whacked the result of inhibition of synthesis of cell membrane m / s and has high Full Weight Bearing against such m / o: Gram (-) aerobic: Haemophilus influenzae (including strains resistant to whacked Naemophilus parainfluenzae, Moraxella (Branhamella) catarrhalis, Neisseria whacked (including strains producing penicillinase and penicillinase-neprodukuyuchi strains), E. bronchitis after previous parenteral cefuroxime sodium) - Sequential therapy: pneumonia: 1,5 g 2 - 3 g / day / v or v / m Single Protein Electrophoresis 48 - 72 h following Indwelling Catheter of 500 mg 2 g / day orally for 7 - 10 days; aggravation hr. Second generation cephalosporins. Staphylococci which are resistant to methicillin, resistant to most antibiotics cephalosporin Most strains of Atypical Squamous Glandular Cells of Undetermined Significance such as: Enterecoccus faecalis, also resistant to cephalosporins. metytsylinstiyki and staphylococci.
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